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**Answer – The "dual‑receptor" ligand used in the model**

In the breast‑epithelial cell model we introduce a **generic small‑molecule ligand that is capable of binding to both estrogen receptors (ERα/β) and the androgen receptor (AR)**.

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| Property | Description |
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| **Solubility** | Water‑soluble at neutral pH; can be dissolved directly in the culture medium without organic solvents. |

*Why this ligand is chosen:*

1. **Non‑toxic to mamm
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