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Der Testosteronspiegel wird im Blut auf einen unteren bis mittleren Wert gebracht.

Verbesserungen zeigen sich meist innerhalb von etwa 3 Wochen wobei eine maximale Verbesserung bis zu 36 Monaten dauern kann. Orale Testosteronpräparate können die Leber belasten da sie direkt über den Magen-Darm-Trakt aufgenommen und in der Leber verarbeitet werden müssen. Dies kann zu Leberentzündungen erhöhten Leberwerten und Leberfunktionsstörungen führen (Johnsen 1978).
Die externe Zufuhr von Testosteron kann die Hypothalamus-Hypophysen-Achse vorübergehend hemmen was die körpereigene Testosteronproduktion reduzieren kann. In einigen Fällen kann es zu einer vorübergehenden Verringerung der Hodenfunktion und reduzierten Spermienproduktion kommen (Khodamoradi et al. 2020).


Die Kapseln werden oral eingenommen und durch die Lymphbahnen direkt in den Blutkreislauf geleitet um die Leber zu entlasten. Da sie die Leber passieren müssen kann ihre Bioverfügbarkeit stark eingeschränkt sein. Dies erhöht d
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