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Whereas this phase is going on you presumably can lower the dosage to 2 to 6mg each two weeks. As the purpose of intake of TB-500 varies so does the dosage for the people. This is primarily due to the quicker response that the body shows after being injected with TB-500. SLAMF1 was also decreased in monocytes and AMs in the Cre+ mice but the variations weren‘t statistically important maybe reflecting inefficient excision of Slamf1 in those cells （Fig. 6A）. As expected for a LysM-Cre strain there was no influence of Cre standing on Slamf1 ex 6D）. The Slamf1fl/fl LysM-Cre+ mice had no vital differences within the variety of myeloid cells in the lung in comparison with Cre- controls （Supplementary Fig. 6F）. Nonetheless the absence of Slamf1 in myeloid cells lead to increased bacterial burden in the lungs and significantly extra infected monocytes CD11c+ non-AMs PMNs and a trend toward more extremely contaminated CD11c- non AMs （Fig. 6B-C）. Many superior |
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